| Date | Time | Home | Opponent | Result | Score | Record |
|---|---|---|---|---|---|---|
| Dec 2, 2021 | 7:30 PM | away | @ Savannah Christian | L | 46-34 | 0-1 |
| Dec 7, 2021 | 7:30 PM | home | Bridges Academy | L | 55-54 | 0-2 |
| Dec 14, 2021 | 7:30 PM | away | @ Coastal | W | 59-30 | 1-2 |
| Dec 28, 2021 | 4:00 PM | neutral | Andrew Jackson | W | 50-41 | 2-2 |
| Dec 30, 2021 | TBD | neutral | Orangeburg Prep | L | 49-47 | 2-3 |
| Jan 3, 2022 | 5:30 PM | away | @ Calvary Day | L | 57-39 | 2-4 |
| Jan 4, 2022 | 7:30 PM | home | Colleton Prep Academy | W | 44-9 | 3-4 |
| Jan 7, 2022 | 7:30 PM | home | Beaufort Academy | L | 54-41 | 3-5 |
| Jan 11, 2022 | 7:30 PM | home | Hilton Head Prep | L | 61-26 | 3-6 |
| Jan 14, 2022 | 7:30 PM | home | John Paul II | L | 48-38 | 3-7 |
| Jan 15, 2022 | 4:00 PM | home | Calvary Day | L | 62-37 | 3-8 |
| Jan 18, 2022 | 7:30 PM | away | @ Thomas Heyward Academy | L | 47-39 | 3-9 |
| Jan 20, 2022 | 6:00 PM | home | Coastal Hurricanes | W | 51-39 | 4-9 |
| Jan 25, 2022 | 6:30 PM | away | @ Holy Trinity | W | 60-21 | 5-9 |
| Jan 28, 2022 | 7:30 PM | away | @ Colleton Prep Academy | W | 59-29 | 6-9 |
| Feb 1, 2022 | 7:30 PM | away | @ Beaufort Academy | L | 50-46 | 6-10 |
| Feb 3, 2022 | 7:15 PM | away | @ Bethesda Academy | W | 51-46 | 7-10 |
| Feb 4, 2022 | 7:30 PM | away | @ Hilton Head Prep | L | 50-36 | 7-11 |
| Feb 5, 2022 | 4:00 PM | home | Savannah Christian | L | 53-33 | 7-12 |
| Feb 8, 2022 | 7:30 PM | away | @ John Paul II | W | 57-35 | 8-12 |
| Feb 10, 2022 | 7:30 PM | home | Thomas Heyward Academy | L | 46-43 | 8-13 |
| Feb 14, 2022 | 6:30 PM | home | Holy Trinity | W | 15-0 | 9-13 |
| Feb 15, 2022 | 7:00 PM | home | Bethesda Academy | L | 50-44 | 9-14 |
| Feb 19, 2022 | TBD | neutral | SCISA AA Playoff Round 1 | 0-0 | 9-14 | |
| Feb 22, 2022 | TBD | neutral | SCISA AA Playoff Round 2 | 0-0 | 9-14 | |
| Feb 24, 2022 | TBD | neutral | SCISA AA Playoff Semi Finals | 0-0 | 9-14 | |
| Feb 26, 2022 | TBD | neutral | SCISA AA Playoff Championship | 0-0 | 9-14 |