| Date | Time | Home | Opponent | Result | Score | Record |
|---|---|---|---|---|---|---|
| Sep 9, 2021 | 5:00 PM | away | @ Hilton Head Prep | W | 12-6 | 1-0 |
| Sep 16, 2021 | 6:30 PM | away | @ Orangeburg Prep | L | 8-6 | 1-1 |
| Sep 23, 2021 | 5:00 PM | home | Colleton Prep Academy | W | 45-8 | 2-1 |
| Sep 30, 2021 | 6:00 PM | away | @ Bethesda Academy | W | 24-6 | 3-1 |
| Oct 7, 2021 | 6:00 PM | home | Hilton Head Prep | L | 18-8 | 3-2 |
| Oct 14, 2021 | 5:00 PM | away | @ Thomas Heyward Academy | W | 27-22 | 4-2 |
| Oct 21, 2021 | 6:00 PM | away | @ Beaufort Academy | L | 24-8 | 4-3 |